THE CONVERSION OF TESTOSTERONE-3-C14 TO C14-ESTRADIOL-17β BY HUMAN OVARIAN TISSUE

The conversion of testosterone-3-C14 to C14-estradiol-17beta by human ovarian tissue.

There is a considerable body of biological data linking testosterone and other 19-carbon steroids with the estrogens. Both ovaries and testes may, under certain circumstances, produce androgens and estrogens (14). The administration of testosterone and other androgens to human subjects leads to an increased urinary excretion of estrogenic material (5-lo), which has been identified as estrone, e...

THE CONVERSION OF TESTOSTERONE-3-Cl4 TO C14-ESTRADIOL-17P BY HUMAN OVARIAN TISSUE* BY BILLY BAGGETT

There is a considerable body of biological data linking testosterone and other 19-carbon steroids with the estrogens. Both ovaries and testes may, under certain circumstances, produce androgens and estrogens (14). The administration of testosterone and other androgens to human subjects leads to an increased urinary excretion of estrogenic material (5-lo), which has been identified as estrone, e...

The synthesis of 17-(methyl-C14)-testosterone and 21-C14-progesterone.

The use of steroid hormones containing tagged atoms promises to have an important part in the study of their metabolism. The relative availability of radioactive Cl4 manufactured in the uranium chain-reacting pile at Oak Ridge has facilitated the synthesis of such compounds containing labeled carbon atoms (1). Through the cooperation of Dr. Konrad Dobriner of the Sloan-Kettering Institute for C...

Conversion of DL-lactate-2-C14 or -3-C14 or pyruvate-2-C14 to blood glucose in humans: effects of diabetes, insulin, tolbutamide, and glucose load.

Conversion of glucose-1-C14 to pectin in the boysenberry.

Many authorities believe that pectins play a dominant r&e in the changes in texture of fruits during the ripening process, although the origin and fate of pectic substances in plant tissues are unknown ((1) p. 273). There is no evidence that in nature pectic substances are formed directly from galactose or galactan ((1) p. 277). To obtain some insight into the mechanism of pectin formation, glu...